Scintigraphic abnormalities in glycogen storage disease

Autor:	J H, Miller, G F, Gates, B H, Landing, M D, Kogut, T F, Roe
Rok vydání:	1978
Předmět:	Adenoma Adult Male Carcinoma Hepatocellular Adolescent Liver Neoplasms Infant Technetium Glycogen Storage Disease Type I Child Preschool Splenomegaly Humans Female Kidney Diseases Colloids Child Radionuclide Imaging Sulfur Hepatomegaly
Zdroj:	Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 19(4)
ISSN:	0161-5505
Popis:	Fifteen patients with glycogen-storage disease type 1 (von Gierke's disease) were evaluated by serial scintigraphy, with a clearly recognizable pattern of an enlarged liver with diminished radionuclide accumulation, splenomegaly with considerably increased uptake and renomegaly. In seven of these patients with GSD-1 scintigraphy demonstrated focal defects of varying size. Small or stable defects suggest benign hepatic adenomata, whereas malignant change occurred in growing large lesions. The potential malignant end-point of hepatic-cell carcinoma in GSD-1 warrants careful serial liver scintigraphy with scintiangiography on a routine basis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::699ae22a4af8da24845980d7a1d5f5f8 https://pubmed.ncbi.nlm.nih.gov/204758 Zobrazit plný text záznamu