Ascites in patients with noncirrhotic nonmalignant extrahepatic portal vein thrombosis

Autor:	M C W, Spaander, H R, van Buuren, B E, Hansen, H L A, Janssen
Rok vydání:	2010
Předmět:	Adult Aged 80 and over Male Venous Thrombosis Adolescent Portal Vein Incidence Ascites Middle Aged Digestive System Neoplasms Survival Analysis Young Adult Humans Female Gastrointestinal Hemorrhage Aged Retrospective Studies
Zdroj:	Alimentary pharmacologytherapeutics. 32(4)
ISSN:	1365-2036
Popis:	To assess the frequency, natural history and prognostic implication of ascites in patients with EPVT and to identify risk factors for this complication.A single-centre retrospective study of consecutive patients diagnosed with noncirrhotic nonmalignant EPVT between 1985 and 2009.One hundred and three patients [35% males; median age 43 (range 16-83) years] were included and followed up for a median time of 5.2 (range 0.9-32.5) years. Twenty-nine (28%) had ascites at the time of diagnosis. Overall survival was 91% at 5 years vs. 80% at 10 years. Survival in patients presenting with and without ascites was 83% vs. 95% at 5 years and 42% vs. 87% at 10 years (P = or0.01). There was no correlation between the presence of ascites and extension of the thrombus into the large splanchnic veins, duration of thrombosis or presence of gastrointestinal bleeding.Ascites is present in a quarter of patients presenting with noncirrhotic nonmalignant extrahepatic portal vein thrombosis. Ascites is a significant and independent prognostic factor and it is associated with a decreased long-term survival.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::697ee73ee10068ef7c5d1b6c8fcfacd9 https://pubmed.ncbi.nlm.nih.gov/20497136 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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