[The behavior of 125I microspheres of serum albumin in the body of rabbits administered the preparation selectively into the renal artery]

Autor:	B Ia, Drozdovskiĭ, R A, Roziev, A Ia, Goncharova, A N, Dedenkov, R A, Brodskiĭ, V M, Petriev
Rok vydání:	1990
Předmět:	Male Drug Carriers Time Factors Kidney Embolization Therapeutic Microspheres Iodine Radioisotopes Renal Artery Injections Intra-Arterial Animals Female Tissue Distribution Rabbits Particle Size Serum Albumin
Zdroj:	Meditsinskaia radiologiia. 35(11)
ISSN:	0025-8334
Popis:	Intraarterial selective injection of serum albumin microspheres into the kidney resulted in embolization of the vessels with microspheres of different sizes. In vivo radiometry made it possible to improve the localization of microspheres and their distribution in the animals' bodies at varying time of observation. Pathomorphological investigations showed optimum sizes of microspheres causing prolonged retention of microparticles at the site of injection without considerable morphological changes of body tissues. The method of using microspheres as a radionuclide carrier was shown to hold promise for therapeutic purposes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::696bc4f00d548154ecd4b4799493ad5e https://pubmed.ncbi.nlm.nih.gov/2259277 Zobrazit plný text záznamu