| Autor: |
Libia, Sanz, Sarai, Quesada-Bernat, Tyelli, Ramos, Luciana L, Casais-E-Silva, Carlos, Corrêa-Netto, Juan José, Silva-Haad, Mahmood, Sasa, Bruno, Lomonte, Juan J, Calvete |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Journal of proteomics. 200 |
| ISSN: |
1876-7737 |
| Popis: |
Micrurus is a monophyletic genus of venomous coral snakes of the family Elapidae. The ~80 recognized species within this genus are endemic to the Americas, and are distributed from southeastern United States to northern Argentina. Although relatively few bites are recorded due to their reclusive nature, semi-fossorial habits, and their occurrence in sparsely populated areas, coral snakes possess powerful venoms that target the cholinergic system and, if early treatment is missed, can cause neuromuscular paralysis, respiratory failure, and death by asphyxiation within hours of envenoming. The to-date proteomically characterized 18 micrurine venoms exhibit a puzzling phenotypic dichotomy, characterized by the toxin arsenal being dominated either by pre-synaptically acting PLA |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full Text from ScienceDirect