Itraconazole synergistically increases therapeutic effect of paclitaxel and
| Autor: | Mahdi, Ghadi, Seyed Jalal, Hosseinimehr, Fereshteh Talebpour, Amiri, Alireza, Mardanshahi, Zohreh, Noaparast |
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| Rok vydání: | 2020 |
| Předmět: |
Technetium Tc 99m Sestamibi
ATP Binding Cassette Transporter Subfamily B Paclitaxel Mice Nude Drug Synergism Antineoplastic Agents Phytogenic Xenograft Model Antitumor Assays Antineoplastic Combined Chemotherapy Protocols Colonic Neoplasms Animals Humans Female Tissue Distribution Whole Body Imaging Itraconazole Radiopharmaceuticals HT29 Cells |
| Zdroj: | European journal of pharmacology. 895 |
| ISSN: | 1879-0712 |
| Popis: | P-glycoprotein (P-gp), is an important efflux pump involved in chemotherapy resistance in human colon cancer. We investigated the efficacy of itraconazole as a P-gp inhibitor and its therapeutic synergistic relationship to paclitaxel through |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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