Taurine Chloramine Suppresses LPS-Induced Neuroinflammatory Responses through Nrf2-Mediated Heme Oxygenase-1 Expression in Mouse BV2 Microglial Cells

Autor: Dong-Sung, Lee, Ki Han, Kwon, Sun Hee, Cheong
Rok vydání: 2017
Předmět:
Zdroj: Advances in experimental medicine and biology.
ISSN: 0065-2598
Popis: The brain is sensitive to the inflammation and oxidative stress that can cause the aging or neurodegenerative diseases. We investigated the anti-neuroinflammatory activities of taurine chloramine (TauCl) on lipopolysaccharide (LPS)-treated mouse BV2 microglia mediated through heme oxygenase (HO)-1 expression. TauCl inhibited the protein expressions of prostaglandin E2 (PGE
Databáze: OpenAIRE