Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue FRET
Autor: | Moa S, Wranne, Anders Foller, Füchtbauer, Blaise, Dumat, Mattias, Bood, Afaf H, El-Sagheer, Tom, Brown, Henrik, Gradén, Morten, Grøtli, L Marcus, Wilhelmsson |
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Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Journal of the American Chemical Society. 139(27) |
ISSN: | 1520-5126 |
Popis: | Förster resonance energy transfer (FRET) using fluorescent base analogues is a powerful means of obtaining high-resolution nucleic acid structure and dynamics information that favorably complements techniques such as NMR and X-ray crystallography. Here, we expand the base-base FRET repertoire with an adenine analogue FRET-pair. Phosphoramidite-protected quadracyclic 2'-deoxyadenosine analogues qAN1 (donor) and qA |
Databáze: | OpenAIRE |
Externí odkaz: |
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