Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue FRET

Autor: Moa S, Wranne, Anders Foller, Füchtbauer, Blaise, Dumat, Mattias, Bood, Afaf H, El-Sagheer, Tom, Brown, Henrik, Gradén, Morten, Grøtli, L Marcus, Wilhelmsson
Rok vydání: 2017
Předmět:
Zdroj: Journal of the American Chemical Society. 139(27)
ISSN: 1520-5126
Popis: Förster resonance energy transfer (FRET) using fluorescent base analogues is a powerful means of obtaining high-resolution nucleic acid structure and dynamics information that favorably complements techniques such as NMR and X-ray crystallography. Here, we expand the base-base FRET repertoire with an adenine analogue FRET-pair. Phosphoramidite-protected quadracyclic 2'-deoxyadenosine analogues qAN1 (donor) and qA
Databáze: OpenAIRE
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