Autor: |
A, Jullienne, C, Calmettes, M S, Moukhtar, G, Milhaud |
Rok vydání: |
1980 |
Předmět: |
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Zdroj: |
Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine. 1(3) |
ISSN: |
0167-1618 |
Popis: |
Carcinoembryonic antigen (CEA) and calcitonin (CT) were extracted from medullary carcinoma of the thyroid (MCT) tissues, fractionated on Sephacryl S-200 and chromatographed on Concanavalin A. CEA purified from MCT is closely related to CEA extracted from colonic tumors. It has an equivalent molecular weight, is a glycoprotein and has a similar electrophoretic mobility in both SDS and basic polyacrylamide electrophoresis. A certain degree of heterogeneity is present in the form of a smaller molecular weight component. Large molecular forms of CT which are present in MCT tissues and which co-elute with the minor component of CEA on Sephacryl chromatography can be separated by Concanavalin A chromatography. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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