Effect of ionic carbohydrate-containing biopolymers on complement activation

Autor:	I V, Nazarova, Y S, Khotimchenko, N M, Shevchenko, V I, Gorbach, P A, Luk'yanov
Rok vydání:	1998
Předmět:	Ions Biopolymers Complement C1 Carbohydrates Complement C3 In Vitro Techniques Complement Activation
Zdroj:	Bulletin of experimental biology and medicine. 131(3)
ISSN:	0007-4888
Popis:	We studied in vitro effects of charged polysaccharides on the classic and alternative pathways of complement activation. The complement system was affected by substances having different charges. Our findings suggest that the conformation of polysaccharide molecules, but not their charge, plays a primary role in the interaction with C1 and C3 complement components followed by initiation of cascade enzymatic reactions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::681d0301f5aa162a285cb1deebb6c015 https://pubmed.ncbi.nlm.nih.gov/11427909 Zobrazit plný text záznamu Full text from SpringerLink