Interpersonal traits of psychopathy linked to reduced integrity of the uncinate fasciculus
| Autor: | Richard C, Wolf, Maia S, Pujara, Julian C, Motzkin, Joseph P, Newman, Kent A, Kiehl, Jean, Decety, David S, Kosson, Michael, Koenigs |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Personality Tests Brain Mapping Adolescent Echo-Planar Imaging Substance-Related Disorders Antisocial Personality Disorder Criminals Neuropsychological Tests behavioral disciplines and activities White Matter Temporal Lobe Article Frontal Lobe Young Adult Diffusion Tensor Imaging nervous system Anisotropy Humans Interpersonal Relations |
| Zdroj: | Human brain mapping. 36(10) |
| ISSN: | 1097-0193 |
| Popis: | Psychopathy is a personality disorder characterized by callous lack of empathy, impulsive antisocial behavior, and criminal recidivism. Here we performed the largest diffusion tensor imaging (DTI) study of incarcerated criminal offenders to date (N = 147) to determine whether psychopathy severity is linked to the microstructural integrity of major white matter tracts in the brain. Consistent with the results of previous studies in smaller samples, we found that psychopathy was associated with reduced fractional anisotropy in the right uncinate fasciculus (the major white matter tract connecting ventral frontal and anterior temporal cortices). We found no such association in the left uncinate fasciculus or in adjacent frontal or temporal white matter tracts. Moreover, the right uncinate fasciculus finding was specifically related to the interpersonal features of psychopathy (glib superficial charm, grandiose sense of self-worth, pathological lying, manipulativeness), rather than the affective, antisocial, or lifestyle features. These results indicate a neural marker for this key dimension of psychopathic symptomatology. |
| Databáze: | OpenAIRE |
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