| Autor: |
M A, Kerr, L M, Loomes, B C, Bonner, A B, Hutchings, B W, Senior |
| Rok vydání: |
2011 |
| Zdroj: |
Methods in molecular medicine. 9 |
| ISSN: |
1543-1894 |
| Popis: |
Human immunoglobulin A (IgA) is found in serum and secretions in several different forms (1), Serum IgA is produced by the bone marrow and is pre-dominately monomeric (M ( r )= 160 kDa). Most of the IgA in secretions (sIgA) is polymeric, predominantly dimeric, comprising two monomer subunits linked together by intersubunit disulfide bonds and a cysteine-rich polypeptide termed J-chain (M ( r )= 16 kDa). Polymeric IgA in secretions, but not in serum, contains an additional heavily glycosylated protein called secretory component (SC) (M ( r )= 70 kDa). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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