Supercritical CO
| Autor: | Chao, Liu, Rui-Rui, Zhang, Yue-Ming, Wang, Jing, Zhang, Qing, Wang, An-Wei, Cheng, Xu, Guo, Xin-Kun, Wang, Jin-Yue, Sun |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Cyclin-Dependent Kinase Inhibitor p21
Dose-Response Relationship Drug Apoptosis Chromatography Supercritical Fluid Cell Cycle Checkpoints Carbon Dioxide Antineoplastic Agents Phytogenic Plant Roots A549 Cells Cell Line Tumor CDC2 Protein Kinase Autophagy Oils Volatile Humans Beclin-1 Croton Drug Screening Assays Antitumor Reactive Oxygen Species Cell Proliferation |
| Zdroj: | Phytomedicine : international journal of phytotherapy and phytopharmacology. 61 |
| ISSN: | 1618-095X |
| Popis: | The use of plant essential oils as pharmaceuticals is a fast-growing market especially in China. Throughout the 20th century, a rapid increase took place in the use of many essential oil-derived products in the medicinal industry as nutraceuticals, medicinal supplements, and pharmaceuticals.The objective of this study was to explore the chemical composition of Croton crassifolius essential oil as well as its potential anti-tumour properties and related anti-proliferative, autophagic, and apoptosis-inducing effects.Supercritical COForty compounds representing 92.90% of the total oil were identified in CCEO. The results showed that CCEO exerted a measurable selectivity for cancer cell lines, especially for A549 with the lowest IC |
| Databáze: | OpenAIRE |
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