Autor: |
V N, Ikoev, M A, Gorbunov, A G, Maĭdaniuk, L G, Karpovich, T V, Kalashnikova, T A, Bektimirov, E V, Karpova, Iu V, Nemtsov, M A, Muntlieva, N I, Kriuk |
Rok vydání: |
1999 |
Předmět: |
|
Zdroj: |
Voprosy virusologii. 44(3) |
ISSN: |
0507-4088 |
Popis: |
Russian cultural concentrated inactivated vaccine protecting from hepatitis A--Hep-A-in-vac was used for immunization of children. The vaccine is slightly reactogenic and completely safe in children aged 3-17 years vaccinated twice in a dose of 0.25 ml. Double immunization of seronegative children with a 1-month interval led to conversion in 89.7% children. In 64.1% children titers of antibodies to hepatitis A virus reached 20 mIU/ml and higher, which indicates rather high antigenic activity of the vaccine. |
Databáze: |
OpenAIRE |
Externí odkaz: |
|