| Popis: |
In the present study a histochemical investigation of the SO and PV nuclei of the hypothalamic-pituitary neurosecretory system are presented at different periods of the water deprivation. The experiments were carried out on laboratory rats (n = 50), weighing 200-250 grams. The experimental and control animals days was maintained at different feeding ration. The control rats (I) were given food and water, the experimental animals (II, III, IV, V) for five days were given the dry food only. Following the 5-day water deprivation, the animals of the Groups III, IV, and V, had given free access to water for 15, 30, and 45 days. In order to investigate histological properties, the animals were rapidly beheaded. In order to reveal a neurosecrete, the 5-10 mm thick slices of the hypothalamus and pituitary gland were stained with the Nissle method. Evaluation of the morphological-functional state of the HPNSS a working scheme of the neurosecretory cycle has been utilized. Analysis of the above data allows concluding that following prolonged water deprivation, recovery level of the structural-metabolic components in the hypothalamic SO and PV nuclei is not uniform. Deeper morphological changes occur in the large-granular region than in the small-granular one, where no significant changes are found; respectively, these cells recover much earlier. Capacity for restoration of the structural-metabolic complex varies and depends on functional properties of the cellular content of these nuclei. |
