| Autor: |
Keita, Tagami, Shigeru, Tanda, Yohei, Satake, Akira, Takeuchi, Yuko, Abe, Takashige, Namima, Hiroaki, Kusunose, Mitsuhisa, Muto, Hiroshi, Nagura |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Gan to kagaku ryoho. Cancerchemotherapy. 39(11) |
| ISSN: |
0385-0684 |
| Popis: |
Primary signet-ring cell carcinoma of the bladder is rare and has a poor prognosis. In addition, there are few successful chemotherapies for it. We report a case of chemotherapy with a docetaxel regimen which was efficacious in a 64-year-old Japanese man suffering from the disease. The onset of bilateral hydronephrosis led to the detection of his bladder tumor, and its pathological diagnosis was signet-ring cell carcinoma(immunohistochemistry showed cytokeratin 7+/20±). He was treated with chemotherapy rather than with surgery because the tumor invaded the abdominal wall and groin. To treat his disease, we performed 2 courses of a chemotherapy regimen comprised of S-1 and cisplatin, but it was not efficacious. We chose docetaxel as a second-line chemotherapy regimen,(60mg/m2, tri-weekly), and a clinical examination including contrast-enhanced CT showed that his disease had successfully responded to the chemotherapy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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