Novel biomarkers in severe community-acquired pneumonia

Autor: Lígia Sarmet Cunha Farah, Rabello, Melissa Tassano, Pitrowsky, Márcio, Soares, Pedro, Póvoa, Jorge Ibrain Figueira, Salluh
Rok vydání: 2011
Zdroj: Revista Brasileira de terapia intensiva. 23(4)
ISSN: 1982-4335
Popis: Community-acquired pneumonia (CAP) is the most common infectious disease requiring admission to intensive care units (ICUs), and achieving an early and precise diagnosis of CAP remains a challenge. Biomarkers play an important role in improving clinical judgment in the emergency room and are adjuvant in evaluating treatment responses. Novel biomarkers, such as cortisol, pro-adrenomedullin and endothelin-1, have been shown to be associated with disease severity and short-term outcomes. This review article focuses on the clinical use of novel biomarkers, severity prediction and treatment monitoring as well as future directions of the field.
Databáze: OpenAIRE