| Autor: |
Burak, Bayraktar, Ebru Şahin, Güleç, Yaşar Bekir, Kutbay, Can, Köse, Esra Bahar, Gür, Ahmet, Demir |
| Rok vydání: |
2021 |
| Zdroj: |
Journal of human reproductive sciences. 15(1) |
| ISSN: |
0974-1208 |
| Popis: |
Follicle-stimulating hormone (FSH) plays a key role in fertility and shows its effect through the FSH receptor (FSHR), which is localized in cells.The aim of this study was to examine pregnancy outcomes and responses to controlled ovarian stimulation according to FSHR polymorphism types.The study was retrospective, and included patients who applied to the University of Health Sciences Tepecik Training and Research HospitalPatients who underwent IVF-intracytoplasmic sperm injection and at the same time studied FSHR gene polymorphism in the genetic unit of our hospital were included in the study.The Kruskal-Wallis test was used for multiple comparisons of continuous variables. The Chi-square test was used for categorical variables between groups.A total of 143 patients who met our criteria were included in the study. 14% (Ser/Ser polymorphism is characterised by a poor ovarian response. Despite this, polymorphisms in the FSHR gene do not seem to affect the results of pregnancy per started cycle, ongoing pregnancy per started cycle, ongoing pregnancy per embryo transfer and live birth per embryo transfer. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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