| Autor: |
B M, Shloznikov, S G, Donich, O A, Grebenchikova, R F, Makhmutov, V V, Likhvantsev, A Iu, Kuznetsov, A I, Peretrukin, E P, Fomchenkov |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny. 109(3) |
| ISSN: |
0365-9615 |
| Popis: |
The antinociceptive properties of dalargin (D) under nembutal anesthesia and artificial ventilation were studied in hemodynamic response to mechanical algesic stimulation in rats. D was introduced i/v (20 micrograms/kg) against a background of myoplegia with Arduan (0.1 mg/kg) and without it. The naloxon (100 micrograms/kg) prevented the protective effects of D. It is considered that injection of D (20 micrograms/kg) on the background of total myoplegia and artificial ventilation prevented hemodynamic response on algesic stimulus. Subsequent dose increase of opium peptide up to 3500 micrograms/kg does not cause amplification of protective properties. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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