| Autor: |
B, Lipový, H, Řihová, M, Hanslianová, Z, Chaloupková, M, Hromaníková, Z, Pavlovský, T, Kempný, I, Suchánek, P, Brychta |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne. 66(3) |
| ISSN: |
1210-7913 |
| Popis: |
Toxic epidermal necrolysis is an autoimmune disease expressed predominantly on the skin and mucous membranes. It is a serious bullous disease manifesting itself by induction of apoptosis in the dermo-epidermal junction. In most cases,it is attributable to the use of some drug. The basic approach to stopping progression of the disease is immunosuppression. Unfortunately, patients with such extensive loss of epidermis and defective mucosa are confronted by a variety of opportunistic, potentially pathogenic microorganisms. Unsurprisingly, infectious complications are today a predominant cause of death in patients thusly affected. Despite thorough review of the literature, we found no comprehensive case report concerning the development of multifocal Aspergillus infection in patients with this disease. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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