| Autor: |
T R, Callaway, R C, Anderson, T S, Edrington, Y S, Jung, K M, Bischoff, K J, Genovese, T L, Poole, R B, Harvey, J A, Byrd, D J, Nisbet |
| Rok vydání: |
2004 |
| Předmět: |
|
| Zdroj: |
Current issues in intestinal microbiology. 5(1) |
| ISSN: |
1466-531X |
| Popis: |
Chlorate kills E. coli O157:H7 and has been proposed as a feed additive to be included in cattle rations immediately prior to slaughter to reduce E. coli O157: H7 populations in the gut. Antibiotic usage is not recommended in cases of E. coil O157:H7-induced hemorrhagic colitis because some antibiotics stimulate increased toxin production. This study was undertaken to determine if chlorate treatment affected toxin production. Pure cultures of E. coil O157:H7 were treated with 1/4 MIC of antibiotics (ampicillin, tetracycline, ceftiofur, gentamicin, monensin, tylosin, penicillin, ciprofloxacin, and novobiocin); toxin production was significantly increased by some antibiotics, but not by chlorate. Studies with mixed fecal bacteria demonstrated that chlorate killed E. coli O157:H7, but again did not stimulate toxin production. Chlorate appears to be an effective method to reduce shiga toxin-producing E. coil (STEC) populations in food animals, but additional studies are warranted before it is used to control infections. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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