An Alternative Pathway to Leukotriene B
| Autor: | Hans, Jagusch, Markus, Werner, Toshiaki, Okuno, Takehiko, Yokomizo, Oliver, Werz, Georg, Pohnert |
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| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Organic letters. 21(12) |
| ISSN: | 1523-7052 |
| Popis: | Oxidized lipids function as tissue hormones in mammals. An important class of these oxylipins are the immunomodulatory leukotrienes (LTs). Besides mammals, marine algae produce bioactive oxylipins, including LTs. The novel acid-labile oxylipin, (5 R,8 S)-dihydroxy eicosatetraenoic acid, from the edible alga Gracilaria vermiculophylla rearranges via a 1,8-diol-forming mechanism to inflammatory LTB |
| Databáze: | OpenAIRE |
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