| Autor: |
Remigio, Vela-Navarrete, Antonio, Alcaraz, Alfredo, Rodríguez-Antolín, Bernardino, Miñana López, Jesús M, Fernández-Gómez, Javier C, Angulo, David, Castro Díaz, Javier, Romero-Otero, Francisco J, Brenes, Joaquín, Carballido, José Mª, Molero García, Antonio, Fernández-Pro Ledesma, José Manuel, Cózar Olmos, José, Manasanch Dalmau, Isaac, Subirana Cachinero, Michael, Herdman, Vincenzo, Ficarra |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
BJU international. 122(6) |
| ISSN: |
1464-410X |
| Popis: |
To comprehensively evaluate the efficacy and safety of the hexanic extract of Serenoa repens (HESr, PermixonWe conducted a systematic review and meta-analysis of randomised controlled trials (RCTs) and prospective observational studies in patients with LUTS/BPH identified through searches in Medline, Web of Knowledge (Institute for Scientific Information), Scopus, the Cochrane Library, and bibliographic references up to March 2017. Articles studying S. repens extracts other than Permixon were excluded. Data were collected on International Prostate Symptom Score (IPSS), maximum urinary flow rate (QData from 27 studies (15 RCTs and 12 observational studies) were included for meta-analysis (total N = 5 800). Compared with placebo, the HESr was associated with 0.64 (95% confidence interval [CI] -0.98 to -0.31) fewer voids/night (P0.001) and an additional mean increase in QThe present meta-analysis, which includes all available RCTs and observational studies, shows that the HESr (Permixon) reduced nocturia and improved Q |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
|
Nepřihlášeným uživatelům se plný text nezobrazuje |
K zobrazení výsledku je třeba se přihlásit.
|
