[The effect of low-dose rate radiation simulating the high-altitude flight conditions on mice in vivo]

Autor: S I, Zaichkina, O M, Rozanova, A Kh, Akhmadieva, G F, Aptikaeva, E N, Smirnova, S P, Romanchenko, O A, Vakhrusheva, S S, Sorokina, V N, Peleshko
Rok vydání: 2007
Předmět:
Zdroj: Radiatsionnaia biologiia, radioecologiia. 47(5)
ISSN: 0869-8031
Popis: In present work, we investigated the peculiarities of the effect of a low-dose rate high-LET radiation that simulates the spectral and component composition of the radiation field formed in the atmosphere at a height of 10 km on mice in vivo. The dose dependence and adaptive response were examined. Irradiation of mice was performed for 24 h a day in the radiation field behind the concrete shield of the Serpukhov accelerator of 70 GeV protons for the time (15-31 days) necessary to accumulate the required doses. The experiments demonstrated that irradiation of mice in vivo in the dose range of 11.5-31.5 cGy leads to an increase in cytogenetic damage to bone marrow cells and induces no adaptive response in bone marrow cells.
Databáze: OpenAIRE