| Autor: |
R, Roberts, T, Bavendam, D B, Glasser, M, Carlsson, N, Eyland, V, Elinoff |
| Rok vydání: |
2006 |
| Předmět: |
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| Zdroj: |
International journal of clinical practice. 60(6) |
| ISSN: |
1368-5031 |
| Popis: |
We evaluated the effect of tolterodine extended release (ER) on patient- and clinician-reported outcomes in a primary care setting. Patients had overactive bladder (OAB) symptoms foror=3 months and were at least moderately bothered by their most bothersome symptom, as indicated on the patient-completed OAB Bother Rating Scale. Patients completed the Overactive Bladder Questionnaire (OAB-q), American Urological Association Symptom Index (AUA-SI), and Patient Perception of Bladder Condition at each visit; investigators completed the Clinical Global Impression-Improvement at week 12. By week 12, there were statistically significant and clinically meaningful decreases on the OAB-q and AUA-SI total and subscale scores (p0.0001). Seventy-nine per cent of patients experienced some improvement in their overall bladder condition. Physicians reported that 68% of patients were 'much improved' or 'very much improved'. For symptom-defined conditions, patient-reported outcomes are a valuable means for determining responses to treatment. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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