| Autor: |
Keon Min, Kim, Min Sun, Lee, Min Seok, Suh, Haniff Shazwan Muhd Safwan, Selvam, Teik Hin, Tan, Gi Jeong, Cheon, Keon Wook, Kang, Jae Sung, Lee |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Medical physicsREFERENCES. 49(3) |
| ISSN: |
2473-4209 |
| Popis: |
Voxel-based dosimetry is potentially accurate than organ-based dosimetry because it considers the anatomical variations in each individual and the heterogeneous radioactivity distribution in each organ. Here, voxel-based dosimetry forThe administered activity ofThe accuracy of the multiple VSV approach increased with the number of dose kernels. The average dose estimation errors of a single VSV with density correction and 20 VSVs were less than 6% in most cases, although organ-based dosimetry using OLINDA/EXM yielded an error of up to 123%. The advantages of the single VSV method with density correction and the 20 VSVs over organ-based dosimetry were most evident in bone marrow and bone-metastatic tumors with heterogeneous medium properties.The single VSV method with density correction and multiple VSV method with 20 dose kernels enabled fast and accurate radiation dose estimation. Accordingly, voxel-based dosimetry methods can be useful for managing administration activity and for investigating tumor dose responses to further increase the therapeutic efficacy of |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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