Increased hippocampal tail volume predicts depression status and remission to anti-depressant medications in major depression
| Autor: | J J, Maller, K, Broadhouse, A J, Rush, E, Gordon, S, Koslow, S M, Grieve |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Psychiatric Status Rating Scales Depressive Disorder Major Remission Induction Age Factors Venlafaxine Hydrochloride Organ Size Citalopram Prognosis Hippocampus Magnetic Resonance Imaging Antidepressive Agents Pattern Recognition Automated Cohort Studies Depressive Disorder Treatment-Resistant Delayed-Action Preparations Sertraline Image Interpretation Computer-Assisted Humans Female |
| Zdroj: | Molecular psychiatry. 23(8) |
| ISSN: | 1476-5578 |
| Popis: | Studies of patients with major depressive disorder (MDD) have consistently reported reduced hippocampal volumes; however, the exact pattern of these volume changes in specific anatomical subfields and their functional significance is unclear. We sought to clarify the relationship between hippocampal tail volumes and (i) a diagnosis of MDD, and (ii) clinical remission to anti-depressant medications (ADMs). Outpatients with nonpsychotic MDD (n=202) based on DSM-IV criteria and a 17-item Hamilton Rating Scale for Depression (HRSD |
| Databáze: | OpenAIRE |
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