Simultaneous

Autor: J, Maclean, N, Fersht, K, Sullivan, I, Kayani, J, Bomanji, J, Dickson, C, O'Meara, S, Short
Rok vydání: 2016
Předmět:
Zdroj: Clinical oncology (Royal College of Radiologists (Great Britain)). 29(7)
ISSN: 1433-2981
Popis: The increasing use of highly conformal radiation techniques to treat meningioma confers a greater need for accurate targeting. Several groups have shown that positron emission tomography/computed tomography (PET/CT) information alters meningioma targets contoured by single observers, but whether this translates into improved accuracy has not been defined. As magnetic resonance imaging (MRI) is the cornerstone of meningioma target contouring, simultaneous PET/MRI may be superior to PET/CT. We assessed whetherTen patients with meningioma underwent simultaneousThere was substantial IOV in contouring. GTV mean KCL: CT/MRI 0.34, CT/MRI+PET(CT) 0.38, CT/MRI+PET(MRI) 0.39 (P = 0.06). CTV mean KCL: CT/MRI 0.31, CT/MRI+PET(CT) 0.35, CT/MRI+PET(MRI) 0.35 (P = 0.04 for all groups; P 0.05 for individual pairs). One observer consistently contoured largest and one smallest. Observers rarely decreased volumes in relation to PET. Most IOV occurred in bone followed by dural tail, postoperative bed and venous sinuses. Tumour edges were qualitatively clearer on PET(MRI) versus PET(CT), but this did not affect contouring.IOV in contouring challenging meningioma cases was large and only slightly improved with the addition of
Databáze: OpenAIRE