[Barrier elements of chromatin domains and nuclear envelope]

Autor:	A N, Shabarina, M V, Glazkov
Rok vydání:	2013
Předmět:	Chromosomal Position Effects Nuclear Matrix-Associated Proteins Nuclear Envelope Animals Humans Insulator Elements Transgenes Chromatin
Zdroj:	Genetika. 49(1)
ISSN:	0016-6758
Popis:	The results of investigating the functions of different barrier elements, including insulators and MARs/SARs and the models of their effect, are described. The functions of neDNA (DNA from the nuclear envelopes) as a barrier element that protects the transgene from position-effect variegation and its interaction with insulators are discussed. The possible mechanisms of the functioning of structural and functional units of eukaryotic chromosomes of different species are suggested.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::6467fcd09d424be7d4eaf83f2c7369d5 https://pubmed.ncbi.nlm.nih.gov/23662422 Zobrazit plný text záznamu