[Possibility of the development of non-transfusion hemosiderosis in beta-thalassemia, caused by association with HLA-linked hemochromatosis]

Autor:	D A, Settarova, S I, Donskov, R P, Manishkina, T K, Krasavtseva, E G, Klinika
Rok vydání:	1990
Předmět:	Adult Male Hemosiderosis Adolescent Genotype Genetic Linkage HLA-A3 Antigen Middle Aged Pedigree HLA-B14 Antigen HLA-B7 Antigen HLA Antigens HLA-B Antigens Child Preschool Humans Thalassemia Hemochromatosis HLA-B35 Antigen Child
Zdroj:	Gematologiia i transfuziologiia. 35(3)
ISSN:	0234-5730
Popis:	The data of HLA-haplotyping were used as an allele marker controlling hereditary hemochromatosis in 23 patients with beta-thalassemia. The results obtained have permitted a conclusion that hemosiderosis in patients with beta-thalassemia may be caused by association of beta-thalassemia gene with hereditary hemochromatosis. Early diagnosis of hyperferremia is of great prognostic importance as the adequate treatment timely conducted can prevent the development of irreversible changes in the patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::644b95c82e32a97f5b03bc0fc4e3a189 https://pubmed.ncbi.nlm.nih.gov/2361583 Zobrazit plný text záznamu