Bioorthogonal SERS Nanotags as a Precision Theranostic Platform for

Autor: Jing, Wang, Duanwei, Liang, Qingqing, Jin, Jie, Feng, Xinjing, Tang
Rok vydání: 2020
Předmět:
Zdroj: Bioconjugate chemistry. 31(2)
ISSN: 1520-4812
Popis: Precise detection and effective treatment are crucial to prolong cancer patients' lives. Surface-enhanced Raman scattering (SERS) imaging coupled with photothermal therapy has been considered a precise and effective strategy for cancer theranostics. Nevertheless, Raman reporters employed in the literature usually possessed multiple shift peaks in the fingerprint region, which are overlapped with background signals from endogenous biological molecules. Herein, we fabricated a new kind of bioorthogonal Raman reporter and aptamer functionalized SERS nanotags. The SERS nanotags demonstrated a strong Raman signal at 2205 cm
Databáze: OpenAIRE