Quantitative analysis of radial peripapillary capillary plexuses in patients with clinically unilateral pseudoexfoliation syndrome
| Autor: | Yasin Sakir, Goker, Hasan, Kızıltoprak |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Retinal Ganglion Cells Optic Disk Retinal Vessels Middle Aged Exfoliation Syndrome Capillaries Tonometry Ocular Cross-Sectional Studies Nerve Fibers Humans Visual Field Tests Female Prospective Studies Fluorescein Angiography Visual Fields Glaucoma Open-Angle Intraocular Pressure Tomography Optical Coherence Aged |
| Zdroj: | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 258(6) |
| ISSN: | 1435-702X |
| Popis: | The aim of this study was to image the radial peripapillary capillary vessel densities (RPCvds) of the affected eyes and fellow unaffected eyes of individuals with unilateral pseudoexfoliation syndrome (PES) using optical coherence tomography angiography (OCTA) and to compare the RPCvds with those of normal age-matched individuals.The eyes were divided into three groups: the pseudoexfoliative material (PXM)-positive eyes of patients with clinically unilateral PES (study eyes), the fellow eyes of the PXM-positive patients (fellow eyes), and the eyes of healthy patients (control eyes). Those patients with glaucomatous findings, including peripapillary hemorrhaging, cupping, notching, focal thinning of the neuroretinal rim, or intraocular pressure readings greater than 21 mmHg, were excluded from the study. The RPCvd (%), peripapillary retinal nerve fiber layer (RNFL) thickness (μm), cup/disc area ratio, rim area (mmThis cross-sectional comparative prospective study included 128 eyes of 88 patients: 40 PXM-positive eyes, 40 fellow eyes, and 48 control eyes. The RPCvds and RNFL thicknesses in the peripapillary region were significantly lower in the study eyes than in the fellow eyes and the control eyes (p = 0.011 and p = 0.011, p = 0.009 and p = 0.004, respectively). There were no significant differences between the fellow eyes and the control eyes with regard to the RPCvd and RNFL values in any region (p 0.05 for all).Lower RPCvds could provoke capillary deficiency and deterioration of the perfusion of the optic nerve head in patients with PES. |
| Databáze: | OpenAIRE |
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