Autor: |
N V, Belitser, M G, Anishchuk, T M, Pozdniakova, O V, Gorkun |
Rok vydání: |
1989 |
Předmět: |
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Zdroj: |
TSitologiia i genetika. 23(3) |
ISSN: |
0564-3783 |
Popis: |
The ultrastructure of resting and stimulated human blood platelets (P) was studied by the transmission electron microscopy. The cells were chemically fixed (using tannic acid and OsFeCN mixture) 1, 3, 5 and 15 min after the addition of ADP and fibrinogen (F). Early changes in P ultrastructure consist in drastic reduction of the electron-dense layer of glycocalyx and in an increase of the plasma membrane permeability. At the early stages of P aggregation the cells contact with each other due to rapidly arising pseudopodia. Later, the extracellular network containing an exogenous F participates in the aggregation process. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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