Geniposide protects against ox-LDL-induced foam cell formation through inhibition of MAPKs and NF-kB signaling pathways

Autor:	Zhi-Qiang, Li, Xiu-Ying, Huang, Chun-Yan, Hu, Zhong-Sheng, Zhu, Yang, Chen, Min, Gong
Rok vydání:	2019
Předmět:	Lipoproteins LDL Male Mice Inbred C57BL Mice Primary Cell Culture NF-kappa B Animals Iridoids Atherosclerosis p38 Mitogen-Activated Protein Kinases Foam Cells
Zdroj:	Die Pharmazie. 74(10)
ISSN:	0031-7144
Popis:	Atherosclerosis (AS) is characterized by the significant accumulation of low-density lipoprotein (LDL)-cholesterol in macrophages that reside in the vessel wall and the resultant inflammatory response. Therefore, inhibition of LDL-induced inflammation is a promising interference for AS. Many traditional Chinese medicine prescriptions have been developed for AS treatment. Geniposide (GEN) is an iridoid glycoside mainly found in
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::63a5f866666c28f4195696bb4117dfc3 https://pubmed.ncbi.nlm.nih.gov/31685085 Zobrazit plný text záznamu