| Autor: |
N K, Rodionova, N P, Atamaniuk, L P, Derevyanko, V V, Tal'ko, A M, Yanina, M V, Shelkovskiy, G V, Kosyakova, O P, Mehed, N M, Gula, A A, Chumak |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Problemy radiatsiinoi medytsyny ta radiobiolohii. (18) |
| ISSN: |
2304-8336 |
| Popis: |
The study objective was to explore the peculiarities of peripheral blood values in rats under the combined influence of 10.0 mg/kg N-stearoylethanolamine (NSE) and 6.0 Gy dose of ionizing radiation to identify the radiomodifying properties of the drug.hematological, statistical.it was found that NSE injection to irradiated rats leads to exacerbation of hematopoietic system disorders indicating to radiosensitizing effect of the substance.The radiosensitizing effect of the drug was established according to qualitative and quantitative abnormalities in peripheral blood values of the rats. Effect of the NSE drug on the rate of recovery processes (i.e. retardation) in the peripheral blood of rats after irradiation was established under these experimental conditions.Meta doslidzhennja – vyvchyty osoblyvosti zmin gematologichnyh pokaznykiv peryferychnoi' krovi shhuriv v umovah kombinovanogo vplyvu N-ctearoi'letanolaminu (NSE) (10,0 mg/kg) ta ionizujuchogo vyprominennja (6,0 Gr) dlja vyjavlennja radiomodyfikujuchyh vlastyvostej preparata. Metody: gematologichni, statystychni. Rezul'taty. Za danyh umov eksperymentu vvedennja NSE oprominenym shhuram pryzvodylo do zbil'shennja oznak urazhennja krovotvornoi' systemy, shho svidchyt' pro jogo radiosensybilizujuchu diju. Vysnovky. V umovah kombinovanogo vplyvu NSE ta odnorazovogo oprominennja na osnovi jakisnyh ta kil'kisnyh zmin gematologichnyh pokaznykiv peryferychnoi' krovi shhuriv vstanovlena radiosensybilizujucha dija preparatu. Za danyh umov eksperymentu vstanovlenyj vplyv preparatu NSE na shvydkist' vidnovnyh procesiv (spovil'nennja) u peryferychnij krovi shhuriv pislja oprominennja. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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