A need for a paradigm shift in focus: From Kt/V

Autor: Zbylut J, Twardowski, Madhukar, Misra
Rok vydání: 2018
Předmět:
Zdroj: Hemodialysis international. International Symposium on Home Hemodialysis. 22(S2)
ISSN: 1542-4758
Popis: Hemodialysis for chronic renal failure was introduced and developed in Seattle, WA, in the 1960s. Using Kiil dialyzers, weekly dialysis time and frequency were established to be about 30 hours on 3 time weekly dialysis. This dialysis time and frequency was associated with 10% yearly mortality in the United States in 1970s. Later in 1970s, newer and more efficient dialyzers were developed and it was felt that dialysis time could be shortened. An additional incentive to shorten dialysis was felt to be lower cost and higher convenience. Additional support for shortening dialysis time was provided by a randomized prospective trial performed by National Cooperative Dialysis Study (NCDS). This study committed a Type II statistical error rejecting the time of dialysis as an important factor in determining the quality of dialysis. This study also provided the basis for the establishment of the Kt/V
Databáze: OpenAIRE