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Autor: | Lucas, Alvizi, Luciano Abreu, Brito, Gerson Shigeru, Kobayashi, Bárbara, Bischain, Camila Bassi Fernandes, da Silva, Sofia Ligia Guimaraes, Ramos, Jaqueline, Wang, Maria Rita, Passos-Bueno |
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Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Epigenetics. 17(13) |
ISSN: | 1559-2308 |
Popis: | Non-syndromic cleft lip with or without cleft palate (NSCLP), the most common human craniofacial malformation, is a complex disorder given its genetic heterogeneity and multifactorial component revealed by genetic, epidemiological, and epigenetic findings. Epigenetic variations associated with NSCLP have been identified; however, functional investigation has been limited. Here, we combined a reanalysis of NSCLP methylome data with genetic analysis and used both |
Databáze: | OpenAIRE |
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