| Autor: |
Keiichi, Sha, Takashi, Shimoda, Yasunari, Matsunari, Masato, Iwata, Toshinori, Horiuchi, Naoko, Kurita, Katsuyasu, Kitaguchi, Katsuji, Hirai, Hitoshi, Furuya |
| Rok vydání: |
2002 |
| Předmět: |
|
| Zdroj: |
Masui. The Japanese journal of anesthesiology. 51(5) |
| ISSN: |
0021-4892 |
| Popis: |
We evaluated the effect of amrinone in 41 patients undergoing off-pump coronary artery bypass grafting(CABG) retrospectively. Amrinone was intravenously administered at the rate of 5 mcg.kg-1.min-1 after coronary artery anastomosis (A 1 group: 11 cases) or after induction of anesthesia(A 2 group: 13 cases). The hemodynamic variables and use of concomitant drugs were compared among A 1, A 2 and the non-amrinone group (control group: 17 cases). Hemodynamics was measured before, during, after coronary artery anastomosis, and after the chest closure. Catecholamine and vasodilator were used to maintain mean arterial pressure (60 mmHg) and cardiac index(3.0 l.min-1.m-2). Mean pulmonary artery pressure, right atrial pressure and pulmonary artery wedge pressure were significantly higher during anastomosis than before anastomosis in control and A 1 group, but no significant changes in these parameters were observed in A 2 group. In addition, these variables increased significantly after chest closure in control group, but were unchanged in A 1 and A 2 groups. Patients with concomitant use of catecholamine and vasodilator in A 2 group were fewer than those in control and A 1 group. In conclusion, in the patients undergoing off-pump CABG, infusion of amrinone was recommended from the end of the induction of anesthesia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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