[Prevention of postoperative scars in otorhinolaryngology: experimental rationale]

Autor: A I, Kriukov, S M, Sharkov, M N, Shubin, E A, Kalashnikova, R B, Khamzalieva, Sh M, Akhmedov
Rok vydání: 2002
Předmět:
Zdroj: Vestnik otorinolaringologii. (2)
ISSN: 0042-4668
Popis: It is demonstrated that in vitro inhibition of fibroblasts proliferation is feasible with the use of 5-fluorouracil. In stimulated growth of fibroblasts, the antiproliferative effect of 5-fluorouracil manifests even in a minimal concentration (2 mcg/ml). Recovery of fibroblast proliferative activity after elimination of 5-fluorouracil occurs in concentration under 63 mcg/ml.
Databáze: OpenAIRE