| Autor: |
G, Radetti, B, Pasquino, C, Castellan, L, Gentili, G, Mengarda |
| Rok vydání: |
1991 |
| Předmět: |
|
| Zdroj: |
La Pediatria medica e chirurgica : Medical and surgical pediatrics. 13(5) |
| ISSN: |
0391-5387 |
| Popis: |
We studied in 10 children (3 boys and 7 girls), affected by precocious puberty and treated for a period of more than 6 months with the GnRH-analog Buserelin, the efficacy of the GnRH test versus the study of spontaneous nocturnal secretion of LH, testosterone and 17 beta-estradiol as a means of testing the gonadotropin suppression. All the subjects have shown a total suppression of LH during the GnRH test as well as a nocturnal profile of LH, testosterone and 17 beta-estradiol of a prepubertal pattern. Clinically all the patients were treated successfully. Considering the effectiveness of both investigations, we conclude that the GnRH test combined with clinical observation is a single and valid means of testing the pharmacological treatment for precocious puberty. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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