How do G-proteins stay at the plasma membrane?

Autor:	G, Milligan, M A, Grassie
Rok vydání:	1997
Předmět:	GTP-Binding Proteins Acylation Cell Membrane Molecular Sequence Data Protein Prenylation Animals Humans Amino Acid Sequence Palmitic Acids Lipid Metabolism Substrate Specificity
Zdroj:	Essays in biochemistry. 32
ISSN:	0071-1365
Popis:	G-protein alpha-subunits are modified by combinations of fatty acyl groups. G-protein gamma-subunits are isoprenylated. These modifications play central roles in membrane association of the G-proteins. Attachment of long-chain fatty acyl chains to G-protein alpha-subunits via a thioester linkage allows the possibility of dynamic regulation of membrane attachment and function.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::632cfe5b4e2898aeef6942c113c523c6 https://pubmed.ncbi.nlm.nih.gov/9493010 Zobrazit plný text záznamu