Subchronic oral administration of acemannan in the rat and dog

Autor: R W, Fogleman, T E, Shellenberger, M F, Balmer, R H, Carpenter, B H, McAnalley
Rok vydání: 1992
Předmět:
Zdroj: Veterinary and human toxicology. 34(2)
ISSN: 0145-6296
Popis: Acemannan is the USAN-accepted name for long-chain polydispersed beta-(1,4)-acetylated polymannose with interspersed O-acetyl groups, with a mannose monomer/acetyl ratio of approximately 1:1. This complex polysaccharide is extracted from Aloe vera (barbadensis Miller); the technical material contains approximately 78% acemannan. Technical grade acemannan was administered po to rats for 14 d at 5% of the diet and for 6 mo at up to 2,000 mg/kg/d, and to beagle dogs for 90 d at up to 1,500 mg/kg/d without significant effect on any parameter measured in either species.
Databáze: OpenAIRE