| Autor: |
Xu-Feng, Liu, Hong-Yi, Chen, Jing, Wang, Su, Yun, Xiao-Qian, He, Xue-Qing, Tang, Ming-He, Sui |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Zhen ci yan jiu = Acupuncture research. 44(5) |
| ISSN: |
1000-0607 |
| Popis: |
To observe the effect of acupuncture at "Shenshu"(BL23)-"Taixi"(KI3)on the levels of serum uric acid (SUA) and expression of renal urate-anion transporter 1 (URAT1) and organic anion transporter 1 (OAT1) proteins in hyperuricemia (HUA) rats, so as to explore its underlying mechanisms in improving HUA.A total of 25 male Wistar rats were divided into 4 groups: control (After modeling, the content of SUA and the expression of renal URAT1 protein (shown by both immunoactivity and WB) were significantly increased (Acupuncture of "BL23" and "KI3" can effectively down-regulate SUA level in HUA rats, which may be related to its effects in down-regulating the expression of URAT1 and up-regulating the expression of OAT1 in the kidney tissue. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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