| Autor: |
J, Hrudka, V, Eis, J, Šach, P, Klézl, S, Schilling, D, Bandke |
| Jazyk: |
němčina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Der Pathologe. 39(1) |
| ISSN: |
1432-1963 |
| Popis: |
We report a case of a 65-year-old man examined for hematuria and neurologic symptoms. Radiologically a tumour of the kidney was suspected, with metastatic involvement of the brain and both lungs. The urologists then performed a cytoreductive nephrectomy.In histopathological examination of the nephrectomy specimen a clear cell renal cell carcinoma (clear cell RCC) was found. However, an additional focus of a high-grade adenocarcinoma was discovered that turned out to be a metastasis of a poor differentiated lung adenocarcinoma. This diagnosis was supported by positive TTF1 and napsin-A as well as good clinical correlations.The article summarizes the differential diagnostic considerations of poor differentiated adenocarcinoma of the kidney, aimed at gross and microscopic morphology, immunohistochemistry and clinical-pathological correlation. A review of literature about a tumour-in-tumour metastasis is included. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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