| Autor: |
J J, Baudon, J L, Fontaine, M, Larrègue, G, Feldmann, R, Laplane |
| Jazyk: |
francouzština |
| Rok vydání: |
1978 |
| Předmět: |
|
| Zdroj: |
Archives francaises de pediatrie. 35(1) |
| ISSN: |
0003-9764 |
| Popis: |
Two familial cases of acrodermatitis enteropathica began at the time of weaning, with characteristic dermatologic lesions and digestive signs, resulting in lack of weight gain: at 13 months of age growth future was evident in the elder child. The anatomic lesions were those of an exophagitis and, in the duodenal mucosa, a dilation of the capillaries of the chorion in the absence of villous atrophy. The ultrastructural study showed inclusions in Paneth's cells, and changes in keratin cells, with intra-cytoplasmic vacuoles and abnormal melanin pigment in the skin. The administration of zinc sulphate induced a rapid recovery of cutaneous lesions and resumption of growth. The interruption of treatment resulted twice in a quite immediate relapse of cutaneous signs in the first patient, which was rapidly reversible with the reintroduction of zinc sulphate. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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