| Autor: |
M M, Bystrova, A N, Britov, V M, Gorbunov, A V, Lebedev, N A, Eliseeva, V A, Metel'skaia |
| Rok vydání: |
1999 |
| Předmět: |
|
| Zdroj: |
Terapevticheskii arkhiv. 71(6) |
| ISSN: |
0040-3660 |
| Popis: |
The study of hypotensive efficacy of high-cardioselective beta-blocker betaxolol, its effects on lipid and carbohydrate metabolism, menopausal syndrome in females with mild and moderate arterial hypertension.20 postmenopausal 45-59-year-old women entered the trial of betaxolol. They had diastolic blood pressure 90-114 mm Hg. Beta-blockers were not contraindicated. Arterial pressure, heart rate, body mass, blood lipid spectrum, glucose and insulin levels were evaluated before the treatment, 1, 3 and 6 months after it.Betaxolol safely and effectively lowered blood pressure. Blood lipid spectrum remained unchanged. A transitory rise in fasting insulin levels did not worsen glucose tolerance despite a small gain in body mass. Menopausal syndrome relieved due to good effect of betaxolol on vasomotor disorders.Betaxolol has a good hypotensive effect in the absence of adverse effects on lipid and carbohydrate metabolism. A reduction of menopausal syndrome was also achieved. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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