| Autor: |
Anna, Eleftheriadou, Thomas, Chalastras, Elisa, Ferekidou, Lambrini, Kyriou, Ioannis, Yiotakis, Zisis, Pappas, Eleftherios, Ferekidis, Dimitrios, Kandiloros |
| Rok vydání: |
2006 |
| Předmět: |
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| Zdroj: |
Anticancer research. 26(3B) |
| ISSN: |
0250-7005 |
| Popis: |
The aim of this study was to examine and compare the value of the serum tumor markers CYFRA 21-1, TPA-M, SCCA and CEA in squamous cell carcinoma (SCC) of the larynx. Moreover, their possible clinical applications were studied.The serum levels of CYFRA 21-1, TPA-M, SCCA and CEA were measured in 79 patients with histologically-proven squamous cell carcinoma (SCC) of the larynx before and after treatment and in 77 healthy volunteers. The association of the results with the clinicopathological characteristics was investigated.The study showed that none of the markers revealed a significant sensitivity; TPA-M indicated a positive correlation with the grade of differentiation. CEA indicated a positive correlation only with distant metastasis.Among the four markers, only TPA-M may play a role in monitoring the success of therapy and follow-up in patients with SCC of the larynx. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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