Postnatal expansion of mesenteric lymph node stromal cells towards reticular and CD34

Autor: Joern, Pezoldt, Carolin, Wiechers, Mangge, Zou, Maria, Litovchenko, Marjan, Biocanin, Michael, Beckstette, Katarzyna, Sitnik, Martina, Palatella, Guido, van Mierlo, Wanze, Chen, Vincent, Gardeux, Stefan, Floess, Maria, Ebel, Julie, Russeil, Panagiota, Arampatzi, Ehsan, Vafardanejad, Antoine-Emmanuel, Saliba, Bart, Deplancke, Jochen, Huehn
Rok vydání: 2021
Předmět:
Zdroj: Nature communications. 13(1)
ISSN: 2041-1723
Popis: Gut-draining mesenteric lymph nodes (LN) provide the framework to shape intestinal adaptive immune responses. Based on the transcriptional signatures established by our previous work, the composition and immunomodulatory function of LN stromal cells (SC) vary according to location. Here, we describe the single-cell composition and development of the SC compartment within mesenteric LNs derived from postnatal to aged mice. We identify CD34
Databáze: OpenAIRE