| Autor: |
C, Chande, Y S, Thakar, S, Pande, A G, Dhanvijay, A M, Saoji |
| Rok vydání: |
2002 |
| Předmět: |
|
| Zdroj: |
Indian journal of pathologymicrobiology. 44(3) |
| ISSN: |
0377-4929 |
| Popis: |
The present study deals with a total of 28 cases of Wilson's disease, 50 normal individuals alongwith siblings and parents of eight cases. Male predominance (18 out of 28 cases), a median age of 11 years and universal presence of Kayser-Fleischer (K. F.) ring marked the cardinal features. Furthermore, 11 patients had hepatic-neural presentation while two had only the K. F. Ring without clinical abnormality. Single Radial Immunodiffusion (SRID) as the absolute quantitative procedure revealed a profound deficiency of ceruloplasmin with the levels ranging anywhere between 0.5 mg/dI to 23 mg/dI amongst the patients of Wilson's disease. The data from siblings and parents also revealed deficiency in 15 out of 23 serum samples when subjected to disc electrophoresis-benzidine screening procedure. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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