Antifungal activity of some substituted pyrimidines
Autor: | J D, McChesney, M, Gonzalez-Sierra |
---|---|
Rok vydání: | 2013 |
Zdroj: | Pharmaceutical research. 2(3) |
ISSN: | 0724-8741 |
Popis: | Several 6-chloro-5-nitropyrimidines were synthesized, and their antifungal activity was tested. Some derivatives were equipotent or superior to amphotericin B in vitro but their relatively high toxicity in mice and their chemical instability discourage further evaluation. |
Databáze: | OpenAIRE |
Externí odkaz: |