[Congenital aplastic anemia, type I]

Autor: R, Jean, D, Dossa, M, Navarro, N, Rizkalla, M F, Lambert, A, Wagner
Jazyk: francouzština
Rok vydání: 1975
Předmět:
Zdroj: Archives francaises de pediatrie. 32(4)
ISSN: 0003-9764
Popis: Case report of a 7 year old girl, anaemic since birth. The anaemia, of variable intensity, is associated with a moderate reticulocytosis. Bone marrow films, show a marked erythroblastosis with conspicuous morphological abnormalities and internuclear chromatin bridges. The erythrocinetic pattern is that of ineffective erythropoiesis. The morphologic features are those of Heimpel and Wendt's type I congenital dyserythropoiesis. The erythrocytes are lysed by some acidified sera, thus showing a membrane anomaly which is unusual in type I. However the characteristics of the lysis are different from those of type II (HEMPAS) erythrocytes.
Databáze: OpenAIRE